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Enantioselective synthesis of isoindolinones
DESCRIZIONE
The present invention relates the asymmetrical synthesis of heterocyclic compounds of pharmaceutical interest. In particular a series of enantioselective methods is described, allowing the synthesis and transformations of isoindolinones of Formula (I), into high yields and enantiomeric excesses >90%
NEED
Asymmetrical synthesis of heterocyclic compounds of pharmaceutical interest
VANTAGGI
Efficient route to biological active isoindolinones
PRINCIPALI APPLICAZIONI
Process
TRL 4
- Tecnologia convalidata in laboratorio
PAROLE CHIAVE
asymmetric synthesis, isoindolinones, active compounds
| Status | Patente Italiana Depósito n. 102015902348105 - 5 Mayo 2015 Concesión n. 102015902348105 - 31 Agosto 2017 Scadenza: 5 Mayo 2015 Patente Europea 16728101.3 - 18 Octubre 2017 Concesión n. 3292102 - 8 Septiembre 2021 Scadenza: 3 Mayo 2036 Convalide Nazionali: Italia, Francia, Germania, Regno Unito. Patente Internacional PCT/IB2016/052507 - 3 Mayo 2016 Publicación n. WO2016/178140 - 10 Noviembre 2016 | |
| Inventores | MASSA Antonio, De Capraris Paolo, Di Mola Antonio |
Classificazione
C - CHEMISTRY; METALLURGYC07 - ORGANIC CHEMISTRY
